You can buy Orlistat (Xenical/Alli) as an over-the-counter alternative to Wegovy in the UK.
However, Orlistat is a very different type of weight-loss medication, and research suggests it’s not as effective as Wegovy in supporting weight loss.
Wegovy and Orlistat are weight-loss medications approved for use in the UK. However, they are different medications with distinct dosing schedules, costs, and mechanisms of action on the body.
Orlistat is a lipase inhibitor. Lipases are gut enzymes that break down fat from food, enabling the gut to transport fat into the body to be burnt for energy or stored in our fat cells for later use.
Orlistat blocks lipases, preventing some of the dietary fat from our meals from being digested. This leads to fewer calories being absorbed, which can support weight loss.
Orlistat is a prescription medication produced by two pharmaceutical companies in the UK:
Wegovy is a weight-loss jab manufactured by Novo Nordisk. It’s a weekly weight-loss injection with semaglutide as the active ingredient.
Semaglutide is a that helps reduce hunger and appetite, allowing you to eat fewer calories, lose weight, and manage your blood sugar levels.
Wegovy is approved in the UK for individuals living with obesity to help them eat fewer calories and lose weight.
The over-the-counter version of Orlistat will cost around £18 a month, so it’s a very affordable medication.
In comparison, buying Wegovy and the injectable pens required for four weeks from Second Nature will cost £229 a month, rising to £299.
Orlistat is an affordable medication that is generally well-tolerated. However, it’s less effective than Wegovy. Wegovy is twice as effective as Orlistat for weight loss after one year.
So, if you’re looking for the most affordable weight-loss pill you can purchase over the counter, then Orlistat could be an option.
However, if you have a higher budget and are looking for the most effective weight-loss injection in the UK, semaglutide is a better choice.
Semaglutide is designed as an additional tool for weight management and, in most cases, shouldn’t be considered a lifelong medication.
Instead, it should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.
Ideally, we’d be able to lose weight without medication and lifestyle changes would be enough to support weight loss in the long term.
We’d generally recommend trying Second Nature’s before considering a weight-loss jab.
Changing your habits is the most sustainable way to achieve long-term weight loss, and it’s also less expensive.
At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.
In 2022, the NHS in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.
Second Nature was more than twice as effective at supporting weight loss than the other four providers.
However, if you’ve decided to try semaglutide (when it’s available) but need support in making positive changes to your lifestyle, Second Nature could be an option for you. But it’s worth noting that we have strict eligibility criteria.
Second Nature has (among the most evidence-based in the UK#p): A review of 56 providers concluded that have been included. They are (of five providers) (
).
Featured Price: Low to High Price: High to Low Avg. Customer Review Newest ArrivalsSort by
Alli is a top weight-loss brand in Turkey,...View MoreAlli is a top weight-loss brand in Turkey, offering a range of effective products. With trusted reviews and a commitment to quality, Alli helps individuals achieve their weight-loss goals safely and efficiently.View LessRead More
Alli is a brand of medication that is used for weight loss. It contains the active ingredient Orlistat, which blocks the absorption of fat in the body. Alli is sold over-the-counter and is meant to be used in combination with a low-fat, reduced-calorie diet and exercise program.
- Alli was launched in 2007 by GlaxoSmithKline.
- It was the first FDA-approved over-the-counter weight loss medication.
- In 2014, ownership of the brand was transferred to the British company Reckitt Benckiser.
- Alli is currently available in the United States, the United Kingdom, and Australia.
Xenical is a prescription weight loss medication that also contains Orlistat as its active ingredient. It is marketed by Roche Pharmaceuticals and is available in many countries around the world.
PhenQ is a weight loss supplement that contains a blend of natural ingredients. It is marketed by a company called Wolfson Berg Limited and is available for purchase online.
Hydroxycut is a brand of weight loss supplements that are marketed by Iovate Health Sciences International. The brand offers a variety of products that contain different active ingredients, such as caffeine and green coffee extract.
Alli Capsules are the brand's flagship product. Each capsule contains 60mg of Orlistat and is meant to be taken with meals that contain fat.
Alli is used for weight loss. It works by blocking the absorption of fat in the body.
Alli is meant to be taken with meals that contain fat. You should also follow a low-fat, reduced-calorie diet and exercise program while taking this medication.
Alli is generally considered safe when used as directed. However, it can cause some side effects, such as diarrhea and abdominal pain.
Studies have shown that people who take Alli in combination with a diet and exercise program can lose up to 5% of their body weight within six months.
No, Alli is not recommended for use during pregnancy or breastfeeding.
Copyright © 2025 Ubuy Co. All rights reserved.
aintoon2ejmj0x9uINTRODUCTBcj0t1MANUFACTURED BY
Cynthia M. Stoddig, PharmD
and
used combination products with Alli for weight loss in combination with a healthy, low-fat, reduced-calorie diet and exercise program.
Cynthia, a native of the United States, returned from abroad with chronic weight gain after trying Alli for a number of months.
The results were mixed, with one study reporting that phentermine can cause a 4.6% weight loss in people who took the combination product, and another found that Orlistat can cause a 4.3% weight loss in people who took the combination product.
Xenical 120mg Capsules, otherwise known as Orlistat 120mg are a cornerstone in the management of obesity. These are segmented by the primary diagnosis (obesity), along with other therapeutic conditions (e.g., anti-obesity agents, weight loss, etc.).
Anti-obesity agents are used in conjunction with a reduced-calorie diet and/or exercise to reduce caloric intake. Orlistat is a lipase inhibitor and works by blocking the enzyme lipase (Type II-lipase) in the body. Lipases are the body’s fast-acting chemical�s main defense mechanisms against parasites, bacteria, and other microorganisms. By inhibiting lipase, Xenical blocks the lipase activity, preventing the lipase from hydrolyzing the triglycerides found in faeces. This helps reduce calorie intake, which can help in weight loss.
Anti-obesity agents are used in conjunction with a reduced-calorie diet and/or exercise to reduce calorie intake, which can help in weight loss. Orlistat is a lipase inhibitor and works by blocking the lipase activity, preventing the lipase from hydrolyzing the triglycerides found in faeces.
Orlistat (Xenical 120mg) reduces fat absorption by inhibiting the triglyceride-dependent enzyme (TGs). This helps remove about one third of the fat from the bloodstream and reduce the risk of pancreatitis. It also blocks the absorption of some fats from the gastrointestinal tract (especially trans fat, which is present in oily body fluids), leading to less absorption. This helps in weight loss.
Orlistat works by blocking the absorption of triglycerides, which are fat-soluble vitamins (A, D, E, and K). The absorption of these vitamins is dependent on fat content and is also inhibited by Xenical. This prevents the fat-soluble vitamins from being absorbed by the body.
Like all medications, Orlistat can cause side effects, although not everybody gets them.
Common Side Effects:–Less Common but Serious Side Effects:Uncommon but Serious Side Effects:Rare but Serious Side Effects:
Allergic Reactions:Seizures
Xenical 120mg Capsules,when used in conjunction with a reduced-calorie diet, can be used for obesity management, including weight loss and weight maintenance.Xenicalworks in your digestive system to block one-third of the fat in the food you eat from being digestedThe daily intake of fat, carbohydrate and protein should be distributed over three main meals.pills can also block the absorption of some vitamins. You may wish to take a multivitamin supplement along with making sure to keep a well-balanced diet, rich in fruit and vegetables.
The active substance isOrlistat. Each capsule contains120 mg of Orlistat
The other ingredients are microcrystalline cellulose (E460), sodium starch glycolate (type A), povidone (E1201), sodium laurilsulfate and talc. The capsule shell consists of gelatine, indigo carmine (E132), titanium dioxide (E171) and edible printing ink.
84 Capsules
Product descriptionXenical 120mg Capsules is an effective weight-loss medication used to treat obesity in those with a high-fat diet and low-calorie diet.
It works by blocking fat absorption in the digestive system, helping to decrease the amount of absorption of one-third of the fat in the food you eat. Orlistat blocker is a type of Orlistat known as a lipase inhibitor. Lipase is carried out in the liver and is used to reduce the amount of fat that is absorbed into the body. Xenical works by blocking fat absorption in the digestive system, helping to decrease the amount of the fat in the food you eat. Orlistat blocker is a lipase inhibitor. Xenical is a prescription-only medication used to treat obesity in those with a high-fat diet and low-calorie diet. It blocks fat absorption in the digestive system, helping to decrease the amount of the fat in the food you eat. Orlistat is a prescription-only medication used to treat obesity in those with a high-fat diet and low-calorie diet. It blocking fat absorption in the digestive system, helping to decrease the amount of the fat in the food you eat. Xenical 120mg is a well-tolerated medication with a low risk of side effects and a low risk of side effects. It is very effective in helping weight loss and weight maintenance for both adults and children. It may cause dizziness, drowsiness or dizziness and have some other side effects like weight gain, sedation and breast tenderness.
The most common side effects of Xenical are the following:
You should also inform your doctor if the to Xenical you are taking changes from your previous level. You should also speak to your doctor about using Xenical for your weight loss for your age treatment.
Store in a cool, dry place away from direct sunlight and out of the reach of children - it will take up - 1 month to get the full benefit. It may also affect the stability of prescribed dosages. Consult your doctor if you are worried about your health.
Not safe for children under 18 years of age.